- Enlisted in the United States Navy and served in the Pacific Theater during World War II. He served on a minesweeper, and was in the Japanese cities of Hiroshima and Nagasaki less than a month after both were destroyed by atomic bombs.
- Was best man at James Doohan's 1974 marriage to Wende Doohan.
- On Star Trek (1966), he played the all-powerful alien Trelane in the episode The Squire of Gothos (1967), and Klingon captain Koloth in The Trouble with Tribbles (1967), both of which aired in 1967. He reprised the role of Trelane for Star Trek: Judgment Rites (1993), returned as Koloth for the episode Blood Oath (1994), and was a regular at Star Trek conventions and cruises.
- Was the first actor ever to sing with Elvis Presley in a motion picture (Love Me Tender (1956)).
- During and following his acting career, he worked with the Motion Picture & Television Fund, and at one point was its administrator and chief fundraiser. He died at age 87 on April 28, 2011 at the Motion Picture & Television Fund's hospital in Woodland Hills, California.
- Best remembered by Star Trek (1966) fans for his role as the Klingon captain Koloth in the iconic episode, The Trouble with Tribbles (1967).
- Following his death, he was interred at Forest Lawn Memorial Park (Hollywood Hills) in Los Angeles, California.
- His first wife, Judith Campbell Exner, professed to be a mistress of President John F. Kennedy. She was also involved with Chicago Mafia boss Sam Giancana during the period she claimed to be Kennedy's mistress. In a 1988 interview, Exner even stated she had arranged meetings between JFK and Giancana. She also said she had met both men through her former lover, Frank Sinatra.
- Ex-wife Judith Campbell Exner also was a lover of Frank Sinatra's, who introduced her to both President John F. Kennedy and Mafia boss Sam Giancana. Even more, according to the New York Times, she arranged meetings between the president and the Chicago mob boss.
- Attended Fagin's School for Drama.
- Brother of R. Wright Campbell.
- Ex-brother-in-law of Susan Morrow and Gary Morton.
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