- Son-in-law of Ron Howard and Cheryl Howard.
- Appeared in The Da Vinci Code (2006) which was directed by his father-in-law, Ron Howard.
- Seth and his wife, Bryce Dallas Howard, became the parents of son Theodore Gabel (b. Theodore Norman Howard Gabel, February 16, 2007).
- Best friend and high school classmate of actor Josh Gad, who is godfather of Theo Gabel.
- Attended New York University's Tisch School of the Arts.
- He is of Ashkenazi Jewish descent on both sides of his family. He was raised under the Italian surname Cosentino, the surname of his stepfather who adopted him.
- Second child, Beatrice Howard (Beatrice Jean Howard-Gabel), was born on January 19, 2012, weighing in at 8 lbs 6 oz.
- Nephew-in-law of Clint Howard.
- Grandson-in-law of Rance Howard and Jean Speegle Howard.
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