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- Meet a child genius named Sheldon Cooper (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon, who is socially impaired.
- A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- A chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- A ranching family in Montana faces off against others encroaching on their land.
- Shaun Murphy, a young surgeon with autism and Savant syndrome, is recruited into the surgical unit of a prestigious hospital.
- Two brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- On the run from a drug deal gone bad, brilliant college dropout Mike Ross finds himself working with Harvey Specter, one of New York City's best lawyers.
- New Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- Anthology series in which police investigations unearth the personal and professional secrets of those involved, both within and outside the law.
- A scrappy, feisty, fiercely loyal Chicago family makes no apologies.
- An anthology series centering on different characters and locations, showcasing different aspects of horror.
- Claire Beauchamp Randall, a nurse in World War II, mysteriously goes back in time to Scotland in 1743. There, she meets a dashing Highland warrior and gets drawn into an epic rebellion.
- The series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- The trials and tribulations of criminal lawyer Jimmy McGill in the years leading up to his fateful run-in with Walter White and Jesse Pinkman.
- Follows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- Follows District 21 of the Chicago Police Department, made up of two different groups: the uniformed cops and the Intelligence Unit.
- Various chronicles of deception, intrigue, and murder in and around frozen Minnesota. All of these tales mysteriously lead back one way or another to Fargo, North Dakota.
- Three different, but related, families face trials and tribulations in their own uniquely comedic ways.
- F.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- Comedy series following the exploits of Det. Jake Peralta and his diverse, lovable colleagues as they police the NYPD's 99th Precinct.
- Follows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- A new FBI profiler, Elizabeth Keen, has her entire life uprooted when a mysterious criminal, Raymond Reddington, who has eluded capture for decades, turns himself in and insists on speaking only to her.
- In a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- When a psychopath commits murders based on novelist Castle's books, Detective Beckett seeks his help to solve the case. He decides to work with her and uses his experiences as research for his novels.