- Joanna's trademark infectious, roaring cackle is her natural laugh.
- In the spring of 2007, she donned Zhora's costume once more, 25 years after the release of Blade Runner (1982), in order to recreate a climactic scene from the film for the fall 2007 Final Cut release of the film. In the original release, a stunt performer played out Zhora's death scene, with the physical differences between the performer and Cassidy very evident (including the stunt person wearing a different wig). For the final cut, Cassidy's head was digitally transposed onto footage of the stunt performer, making the death scene fit continuity. Cassidy herself suggested this be done; she is captured on video making the suggestion during filming of a retrospective interview.
- Elected to the 2007-2008 Screen Actors Guild National Board of Directors.
- Was replaced by Paula Prentiss after two weeks of filming on The Stepford Wives (1975).
- She auditioned and won the title role for the television series Wonder Woman (1975), but ended up losing it to Lynda Carter. They were both considered for the role of Captain Katherine Janeway on Star Trek: Voyager (1995).
- She has appeared in three films that have been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: Bullitt (1968), Blade Runner (1982) and Who Framed Roger Rabbit (1988).
- She has two children by her now ex-husband Dr. Kennard Kobrin: A daughter Naomi Kobrin (B. December 18, 1964) and a son Daniel Kobrin (B. December 29, 1970).
- Studied art for one year at Syracuse University.
- Has appeared in episodes of three different series with Robert Foxworth: Falcon Crest (1981), Six Feet Under (2001) and Star Trek: Enterprise (2001).
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