- There's a very well made documentary film (from 2003) on H. H. Holmes. Highly recommend and will give you chills.
- He was able to put his surgical training to good use by selling the stripped and monted skeletons of his victims to local anatomy schools!
- First began using the alias "H.H. Holmes" while engaging in shady business deals and promotions.
- He was one of the first documented serial killers before that term was even used.
- Great-great-grandfather of Jeff Mudgett.
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