- Daughter is Mary Jo Sanders, who is a professional boxer.
- Son Charles Sanders Jr, played college football at Ohio State, and had a brief stint in the NFL.
- Professional football player. Tight end with the Detroit Lions, 1968-1977.
- Inducted into the Pro Football Hall of Fame in 2007.
- Works for the Detroit Lions in the Scouting Department (June 2006)
- He lost his mother when he was 2. In his induction speech in the Pro Football Hall of Fame in 2007, he said: "Hi, Mom. Thank you for the ultimate sacrifice. This day belongs to you.".
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