When Manimal transforms into an animal, his clothes are shown to disappear and are nowhere to be seen. When Manimal transforms into a panther his clothes are torn apart but when he transforms back they are perfectly intact. They reappear even when Manimal is unconscious.
A bit strange for a cop, Brooke had a purse seemingly "permanently fused" to her shoulder. Whenever she was running around after bad guys, her purse was inconveniently dangling at her shoulder. She kept her gun in her purse, contrary to other lady cops, who carried it in a holster.
Although visually appealing for they match its fangs, a black panther's claws aren't white, as seen during J.C.'s metamorphosis.
Whenever Jonathan turned into a bird his hands became talons. His feet should have turned into talons and his hands and arms to wings.