The stardate marking the Vesuvi Event (54303.1) places the storyline approximately two years before the events of Star Trek: Nemesis (2002) (56844.9), although the movie was released nine months after this game.
Despite the appearance of official references like the U.S.S. Enterprise, Captain Picard, and Lieutenant Commander Data, this storyline is not considered official in the franchise, although, the fact of using the U.S.S. Sovereign as prototype ship (first of the class) of the U.S.S. Enterprise is widely accepted and referenced to in several official and fan-made websites.
The title "The Drawn Line" is a reference to Picard's line in Star Trek: First Contact (1996) when talking about the Borg: "They assimilate entire worlds and we fall back. Not again. The line must be drawn here! This far, no further!" In this case, it's the Cardassians who push through Federation lines.
The game takes place from 2377 to 2378.