Kimble, in Oklahoma, has hitched a ride, and speculates on the character of the driver. When they get to a diner, a series of circumstances involving police requires Kimble to assume the identity of the driver, Leonard Hull (actor John Milford), who gets away. Kimble is surprised to learn that Hull is a witness in a major prosecution of organized crime figure Buddy Blackburn.
Though Blackburn is never on screen, he is a huge influence lurking in the background. Blackburn has sent a hit man to kill Leonard Hull and his estranged wife (actress Norma Crane) to prevent Mr. Hull from testifying against him, and just in case Mrs. Hull might have been told something.
The sheriff (actor Ed Asner), believing Kimble to be Hull, takes him to see "his wife" Mrs. Hull at a motel where she is in protective custody. Kimble is surprised when Mrs. Hull does not report him as an impostor, but instead tries to coerce him into helping her escape the police and Blackburn. By the time the real Leonard Hull shows up and is detained by police (including actor James Doohan, Scotty on Star Trek), Kimble and Mrs. Hull have escaped, but they face danger every step of the way.