According to many, Hugh Laurie fooled many people (unintentionally) with his made-to-order American accent. However, in this episode, at about the 8:00 mark, he opines: "...either way, this kid's gonna be picking up his diploma in diapers and a wheelchair." His accent fails just enough to say, "...either way, this kid's gonna be picking up his diploma in diapahs and a wheelchair."
One of the lacrosse teams at the beginning of the episode has the colors (maroon and white) and the mascot (Tartans) of Carnegie Mellon University. Additionally, Dan's parents and others also wear Tartan clothes while watching the game.
When House is served a legal notice by his patient, he comments about his being too cheap to pay for the notice to have the notice served. At this moment they are standing in front of the entrance to the Witherspoon Wing. Reese Witherspoon starred in Legally Blonde which was about a blonde attorney challenging stereotypical notions regarding her intellect. This may be to hint that the patient has underestimated Dr. House's intelligence and that a trick to punctuate the same is coming up. He then cunningly declines treatment to the patient because he has been served the notice like all of his previous doctors.