The magazine that Michael Scofield shoves down the sewer has actress Roselyn Sanchez on it. Show co-producer Brett Ratner previously directed Rush Hour 2 with Sanchez co-starring.
Michael's birthday is given as 9/8/78. Using the American dating system, this would make him a Virgo. The actor was born in 6/2/72, a Gemini, more than 6 years older than the character.