First appearance of Carl (H. Jon Benjamin)
The restaurant where Meg and Mayor dine is named "Qu'est-ce que pue Restaurant" which evidently translates from French as the "What Stinks? Restaurant".
According to the DVD commentary, Peter and Lois' band, "Handful of Peter," was originally going to be named "Mouthful of Peter," but the censors didn't go for it.
The title is based on the highest inside White House source used by Bob Woodward and Carl Bernstein during their Watergate investigations while working for the Washington Post in the early 1970's and an X-rated movie.
The Peter and Lois naked sofa scene when Brian and Stewie walk in is heavily edited on some channels in syndication. There is black underwear added and the entire "...knocking on the back door" comment asked by Lois is removed. Brian and Stewie quietly walk back out the door without any dialogue.