According to writer and director Noburo Iguchi, the idea for The Machine Girl went back to a simple idea he had about a one-armed girl in a bikini looking for revenge. The idea for the machine gun arm came later.
Some of the actresses in this film are pornstars.
The family kami (god) of the killers is Hanzo Hattori. Hatori Hanzo was a famous ninja and is often referenced in various fiction and entertainment.
The voice cast for the English language dubbed version, uncredited in the film, but credited on the DVD is: Brina Palencia (as Ami), Robby Sharpe (as Hiroshi), Brandon Potter (as Kaneko), Wayne Grayson (as .Kitamura), Bella Hudson (as.Masako), Evelyn Lanto (as.Miki), Jason Griffith (as Ryota / Various), Charles Bunting (as Ryuji), Tom Wayland (as Shinsuke / Teppei / Yakuza), Christopher Kromer (as Sho), David Wills (as Suguano), Kevin Collins (as Suguru), Dara Seitzman (as Sumire), Herb Lawrence (as Sushi Chef), Drew Aaron (as Takeshi / Teppei), Stephanie Sheh (as Yoshie), Michael Sinterniklaas (as Yu), Christina Shipp (as Yumiko / Old Lady), Dan Green (as Yusume).