Lazaretto was filmed entirely following social distancing regulations during the 2020 Covid-19 lockdowns. Each actor filmed themselves on their phones and was directed via Zoom or FaceTime.
Christina Wren, Peter Porte and Anisha Nagarajan were friends in college.
Christina Wren and Harry Lennix have worked together in Man of Steel, Batman v Superman, Rehabilitation of the Hill and Lazaretto.