It is fitting that Chris is playing Jame Gumb as that was Seth Green's inspiration for Chris' voice.
Aired the same night as The Simpsons episode Habeas Tortoise (2022). Both had a scene involving red "conspiracy" yarn and jokes about calamari.
In the first story, Chris portrays Buffalo Bill in the Silence of the Lambs. Seth Green has gone on record as basing Chris's voice on that of Buffalo Bill.
Many iconic scenes from 'American Beauty' have already been parodied in earlier episodes, including the dream sequence at the school assembly and the plastic bag in the wind.
The box with the cow-like pattern on it Chris is carrying in the The Silence of the Lambs (1991) segment is from the computer maker Gateway 2000, later just Gateway, which was acquired by Acer in 2007.