Ethan mentions seeing Rembrandt's 'The Anatomy of Dr. Tulip'. In 1632 Rembrandt painted 'The Anatomy Lesson of Dr. Nicolaes Tulip'. It depicts several medical professionals looking on as Dr. Tulip displays a cadaver's partially dissected arm and hand. The painting is of a real, albeit staged, event; some of the Drs paid to be in the painting.
Dr Hunt walks under a bridge between two buildings that says Tri Store Bridge. This is actually located in Rhode Island, not Philadelphia. That must be where they filmed.
Abigail Hawk plays the Police Commissioner's secretary in Blue Bloods.