- McGarrett and Chin Ho try to rescue and protect a federal witness on the run from assassins, while Danny tries to get to the bottom of his daughter and ex-wife's carjacking.
- Danny's ex Rachel and daughter Grace are the victim of a car-jacking. As the Mercedes was abandoned, he assumes it must be on account of Grace's stepfather Stan Edwards's business, yet learns the dirty party is a corrupt commissioner. Steve and Chin must find and rescue Julie Adelman, the former accountant of and key witness against Baja drug cartel baron Aaron Brenner, who arranged two uniformed fake cops to kidnap her and eliminate U.S. Marshall Frank Moore. After a commando style mountain jungle rescue, they must deal with the hard to identify 'cleaner' (backup-killer).—KGF Vissers
- When the sole witness in a high-profile murder case disappears, Five-0 must head into the jungle to locate and protect her from assassins who are closing in fast.—CBS Publicity
- Five-0's latest case involves the only witness in a high-profile murder case who's gone missing. They must find her and keep her safe from those who want her dead.
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