The title of the episode is the title of the Inhumans-related story in the comic book issue Amazing Spider-Man Vol 1 #62.
Karnak's clothes on Earth are reminiscent of his more recent attire in the comics.
Kekoa Kekumano briefly appears as a worker at the food truck where Medusa and Louise eat. He also makes regular appearances in Hawaii-Five-0 (2010) as a character that ends up working at a food truck.