This is the first episode in which Jesse Rollins is not played by Kelli Giddish's real son. They have a pair of twins portraying the role now.
This is Chief Dodds' first episode of season 19, with his last appearance being in the season 18 finale.
"Gone Baby Gone" is also the name of a 1998 novel and its 2007 film adaptation.
Faith Logan has had a number of uncredited roles over the course of the series:
- Episode 19.9 Gone Baby Gone (2018) - Mall Vendor (uncredited)
- Episode 18.5 Rape Interrupted (2016) - Victoria McCoy (uncredited)
- Episode 18.1 Terrorized (2016) - Pedestrian (uncredited)
- Episode 17.23 Heartfelt Passages (2016) - C.O. McCoy (uncredited)
- Episode 17.22 Intersecting Lives (2016) - C.O. McCoy (uncredited)
- Episode 17.14 Nationwide Manhunt (2016) - Gallery Member / Client (uncredited)
- Episode 17.13 Forty-One Witnesses (2016) - Client / Gallery Member (uncredited)
- Episode 17.7 Patrimonial Burden (2015) - Young Wife (uncredited)