Matt Lintz takes over the role of Henry after the time jump in this episode. His little brother Macsen Lintz previously played this part on the show before the time jump. There have now been three Lintz siblings on the show following Madison Lintz who portrayed Sophia in the first two seasons.
The toy Sheriff that Michonne (Danai Gurira) finds was created based on a Season 3 Poster featuring Rick (Andrew Lincoln).
In this episode Andrew Lincoln is removed from the Opening Credits for the first time since Season One and Lauren Cohan is removed for the first time since Season Three. Khary Payton is also promoted to Series Regular in this episode.
Writer Eddie Guzelian came up with the idea for the walker growing through the tree with worms in him. He sent Greg Nicotero pictures of what inspired him, a tree growing around a bicycle.
Henry is taking on comic book Carl's role while Ezekiel is taking on comic book Rick's role (both still alive after the time jump)