The opening sequence has been revised to show cast changes: Fiona is no longer featured; now it's Debbie pulling Frank out of the bathroom and then going to the toilet. Debbie wrapping Liam in toilet paper has been replaced with Liam doing the same to Franny. The couple having sex are now Ian and Mickey, then Lip and Tami.
The title of the episode comes from Shakespeare's Henry V: "We few, we happy few, we band of brothers." It is one of the most well-known lines from the St. Crispin's Day speech, in which Henry rallies his men to fight in the Battle of Agincourt, where his army is vastly outnumbered by the enemy.
Season 10 marks the return of Noel Fisher to the regular cast; however, his character Mickey Milkovich does not appear until the second episode. Fisher had not been a regular cast member since the end of season five, although he made several guest appearances in the interim. Mickey also appears in this season's updated opening credits sequence.
Fiona is no longer in the intro for season 10.